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Matched antibody pairs are sets of antibodies that are known to be capable of detecting different epitopes on the same protein antigen; they can be used together for the capture and detection of a single antigen in an immunoassay.
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The protein encoded by this gene belongs to the short-chain dehydrogenases reductases (SDR) family which function as NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds such as quinones prostaglandins and various xenobiotics Alternatively spliced transcript variants have been found for this gene
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Each vial contains 75 ng of recombinant Rat MMP9 / MMP-9 / CLG4B. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 1250 pg/mL is recommended.
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Enables cysteine-type endopeptidase inhibitor activity protease binding activity and virus receptor activity Involved in several processes including autocrine signaling paracrine signaling and regulation of cellular protein metabolic process Located in cytoplasmic vesicle extracellular exosome and nucleus
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This gene encodes an immunoregulatory cytokine produced primarily by activated Th2 cells This cytokine is involved in several stages of B-cell maturation and differentiation It up-regulates CD23 and MHC class II expression and promotes IgE isotype switching of B cells This cytokine down-regulates macrophage activity thereby inhibits the production of pro-inflammatory cytokines and chemokines This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils This gene IL3 IL5 IL4 and CSF2 form a cytokine gene cluster on chromosome 5q with this gene particularly close to IL4
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This gene encodes a protein initially identified as a thyroid-specific transcription factor The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis Mutations and deletions in this gene are associated with benign hereditary chorea choreoathetosis congenital hypothyroidism and neonatal respiratory distress and may be associated with thyroid cancer Multiple transcript variants encoding different isoforms have been found for this gene This gene shares the symbol alias TTF1 with another gene transcription termination factor 1 which plays a role in ribosomal gene transcription
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This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate the mature protein, which plays a role in left-right asymmetry determination of organ systems during development. This gene is closely linked to both a related family member and a related pseudogene.
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This gene encodes a serine threonine-protein kinase that play a central role in mitosis The encoded protein functions in part by phosphorylating members of the mitotic checkpoint complex and activating the spindle checkpoint This protein also plays a role in inhibiting the activation of the anaphase promoting complex cyclosome This protein may also function in the DNA damage response Mutations in this gene have been associated with aneuploidy and several forms of cancer Alternate splicing results in multiple transcript variants
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The Meso Scale Discovery U-PLEX Human A2M Assay is a multiplex immunoassay kit that enables simultaneous quantitative measurement of Alpha-2-Macroglobulin (A2M) in human serum plasma and cell culture supernatants This electrochemiluminescent assay utilizes MSD s proprietary SECTOR Imager and provides high sensitivity a broad dynamic range and requires low sample volume The kit includes a 96-well plate coated with capture antibodies detection antibodies calibrators and diluent This assay allows for efficient and reproducible quantification of the A2M biomarker
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The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants.
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Enables cadherin binding activity. Predicted to be involved in regulation of actin polymerization or depolymerization. Predicted to act upstream of or within isotype switching. Located in actin cytoskeleton, cytoplasm, and plasma membrane.
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This gene encodes a protein that is localized to the nucleolus. Expression of this gene is induced by estrogens and Myc protein and is a marker of poor patient survival in breast cancer. Alternative splicing results in multiple transcript variants.
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A DNA sequence encoding the human TGFB1 (P01137)(Met1-Ser390) was expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 1; A DNA sequence encoding the human GARP (Q14392) (Met1-Asn627) was expressed with a polyhistidine tag at the C-terminus, constructed the plasmid 2. The two plasmids were co-expressed and the TGF Beta 1 & GARP Heterotrimer was purified.
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CD70 also named CD27 ligand (CD27L) is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7 CD70 is a cytokine that binds to CD27 Plays a role in T-cell activation Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells
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Each vial contains 39 ng of recombinant CD171. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 3 ng/mL is recommended.
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